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16 December 2002
Testosterone Clinical Trial To Explore Sexual Desire 
For millions of women, a lack of sexual desire is often an unfortunate consequence of menopause, and can impact a woman's relationship with her partner. Now, new clinical trials at Cedars-Sinai Medical Center may provide hope for many women in the Los Angeles area, as participants are being sought for a study of a new investigational therapy designed to increase sexual interest in women who have experienced a decline in libido after menopause. "An estimated one in three American women suffer from low sexual desire, making it the most common sexual problem in women," said Glenn Braunstein, M.D., Chairman of Medicine at Cedars-Sinai Medical Center. "No medications are currently approved by the U.S. Food and Drug Administration for the treatment of diminished sexual desire. These clinical research studies may lead to a new way to help many women regain a satisfying sex life." Lack of libido often manifests itself as a lack of interest in sexual activity (i.e. lack of receptivity and/or low activity), or the absence of sexual thoughts or fantasies, which can lead to interpersonal difficulties. Many women experience a decline in sexual desire when hormone levels fall following menopause.
This decline in the desire for sex is often accompanied by other sexual problems, such as difficulty achieving orgasm. A study has shown that nearly 40 percent of women experience a decrease in libido during menopause. The clinical trials will investigate whether very low levels of testosterone administered via a thin, nearly transparent patch will increase libido. The patch is worn discreetly on the abdomen and replaced every three to four days. The study is being conducted at sites throughout the U.S., Canada and Australia. To participate in the study, women should have undergone natural menopause, be taking hormone replacement therapy, and be concerned by their decline in sexual desire. Please call 310-423-3850 or 1-866-409-6626 to learn more about participating in this research.
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