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16 July 2004
Endo Risk Linked To Diet?

Women may be able to lower their risk of endometriosis by eating more fresh fruit and green vegetables. But, eating red meat and ham appears to increase their risk, according to a study published in the journal Human Reproduction. The researchers in Milan have now called for a study to further investigate the possible links between diet and endometriosis.

Lead researcher Dr Fabio Parazzini from the University of Milan, explained the study: "We asked women about their diet in the year leading up to the interview. In particular, we asked how many times a week they ate portions of selected dietary items, including the major sources of retinoids and carotenoids in the Italian diet. We also asked about their alcohol and coffee consumption. We divided their intake into portions approximating to low, intermediate and high intake of the various dietary factors. What we found was that there was a 40% relative reduction in risk of endometriosis in women with higher consumption of green vegetables and fresh fruit. But, for those with a high intake of beef, other red meat and ham, there was an increase of about 80-100 percent in relative risk."

There was no significant link between endometriosis and consumption of milk, liver, carrots, cheese, fish, whole-grain foods, coffee or alcohol and no association with butter, margarine or oil.

"With a prevalence of 5% in endometriosis in Italy, this means that if our findings are confirmed in prospective studies, we have the potential to cut the prevalence of endometriosis to around 3-4%, which would mean about 200,000 prevalent cases (and about 10,000 new cases a year) fewer in Italy and probably 800,000 fewer prevalent cases in Europe.

The association between vegetables, fruit and meat was unlikely to be due to chance because the researchers analysed several dietary items. However, it was possible there was a 'healthy woman' effect as a high intake of green vegetables, fruit and fish may be generally indicators of more health-conscious attitudes. Also, women who paid closer attention to their health may be more likely to have endometriosis diagnosed.

"However, despite these limitations, our study does suggest that there is some link between diet and risk of endometriosis and indicates that we now need a proper prospective interventional investigation to study these factors. Endometriosis is a distressing condition that affects the quality of life for many women and if there are adjustments that can be made in the diet to lower the risk it is vital that we gain really firm evidence about which foods protect and which foods increase risk," said Parazzini.


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